Tom Hanks est une grande vedette. - Tom Hanks is a big star.
Notice that "vedette" is one of the few French professions that is always feminine.
Expressions: mettre en vedette - to give someone star billing, to spotlight, highlight; avoir la vedette - to have top billing, be in the limelight; voler la vedette - to steal the show; en vedette américaine - as a special guest star
(click the little graphic below to hear the Mot du jour pronounced)